Do not take St John's wort, the herbal remedy for depression, while you're taking rivaroxaban
39 Published case reports of these interactions include subtherapeutic dabigatran levels without thrombosis due to intervention in patients on concomitant carbamazepine 56 and thrombotic adverse Drug-Drug Interactions Between Ritonavir-Boosted Nirmatrelvir (Paxlovid) and Concomitant Medications
Major: Highly clinically significant
Avoid co-administration, reduce substrate dose, monitor for adverse effects and toxicity
Results: Rivaroxaban did not interact with midazolam (CYP3A4 probe substrate)
You may be at higher risk of bleeding if you take XARELTO ® and have certain There are 9 disease interactions with Biktarvy (bictegravir / emtricitabine / tenofovir alafenamide) which include: hepatic dysfunction
See the list of drugs that interact with Rivaroxaban
Side effects include headache, nausea, abdominal pain, diarrhea, indigestion, and dizziness
It also interacts with blood thinners and medications that can affect heart rhythm
Because the body metabolizes fluconazole in the liver, interactions can occur if you take fluconazole along with other medications that are also metabolized in the liver
Rivaroxaban is a substrate of CYP3A4/5, CYP2J2, and the P-gp and ATP-binding cassette G2 (ABCG2) transporters
loss of bladder control
Avoid combinations; the risk of the interaction outweighs the benefit
hyperbilirubinemia
Cranberry may also inhibit CYP2C9, but evidence is conflicting
In addition, use caution in high risk patients with multiple confounding risk Pharmacokinetic Interaction: Fluconazole is a moderate inhibitor of CYP 3A4 Quinidine is a CYP 3A4 substrate ∴↑ Quinidine levels Rivaroxaban 20 mg po daily for Afib Digoxin 0
Always consult your healthcare provider before starting or stopping any medication
If you have kidney disease, you should talk to your doctor before using rivaroxaban together with fluconazole
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances
No interaction is expected with edoxaban
Always consult your healthcare provider before starting or stopping any medication
Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan
There are 4 disease interactions with allopurinol which include: bone marrow suppression; The relevance of a particular drug interaction to a specific individual is difficult to determine
Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan
This can lower the risk of heart attack and stroke
8-fold, tezacaftor exposure by 4
Moderate Moderate See more Conversely, fluconazole is a moderate CYP3A4 inhibitor, which would be
The triazole antifungals fluconazole and voriconazole inhibit CYP2C9 and can increase the risk of serious bleeding in patients taking warfarin
The administration of fluconazole 400 mg (given for 4 days) significantly
Summary: Drug interactions are reported among 647 people who take Fluconazole and
This is when a medication reacts with one or
A very serious allergic reaction to this drug is rare
They're not tested in the same way as pharmacy and prescription medicines
This is because XARELTO ® is a blood thinner medicine (anticoagulant) that lowers blood clotting
Always consult your healthcare provider before starting or stopping any medication
Fluconazole is an effective antifungal agent that may be used to treat certain fungal or yeast infections
Rivaroxaban causes bleeding, as can Zanubrutinib ; concurrent use might increase the risk of developing this effect
Avoid co-administration, reduce substrate dose, monitor for adverse effects and toxicity
Results: Rivaroxaban did not interact with midazolam (CYP3A4 probe substrate)
It belongs to a class of drugs called azole antifungals
Increasing age, female sex, cardiac disease, and some metabolic disturbances (notably hypokalaemia) predispose to QT prolongation
Rivaroxaban is a substrate of CYP3A4/5, CYP2J2, and the P-gp and ATP-binding cassette G2 (ABCG2) transporters
Sertraline (Zoloft) is a medication prescribed to treat health conditions like anxiety and depression
There’s not a lot of evidence about how much of an issue this interaction may be
muscle spasm or jerking of the arms and legs
Does fluconazole interact with my other drugs? Enter other medications to view a detailed report
Gas
The relevance of a particular drug interaction to a specific individual is difficult to determine
Applies to: fluconazole and rivaroxaban
seizure disorders